Plus Therapeutics (NASDAQ:PSTV – Get Free Report) and Dyne Therapeutics (NASDAQ:DYN – Get Free Report) are both medical companies, but which is the superior business? We will compare the two businesses based on the strength of their analyst recommendations, valuation, institutional ownership, risk, profitability, dividends and earnings.
Analyst Ratings
This is a breakdown of current ratings and price targets for Plus Therapeutics and Dyne Therapeutics, as provided by MarketBeat.com.
| Sell Ratings | Hold Ratings | Buy Ratings | Strong Buy Ratings | Rating Score | |
| Plus Therapeutics | 1 | 1 | 4 | 1 | 2.71 |
| Dyne Therapeutics | 1 | 3 | 10 | 4 | 2.94 |
Plus Therapeutics presently has a consensus target price of $7.75, indicating a potential upside of 1,416.63%. Dyne Therapeutics has a consensus target price of $34.93, indicating a potential upside of 65.09%. Given Plus Therapeutics’ higher possible upside, analysts clearly believe Plus Therapeutics is more favorable than Dyne Therapeutics.
Earnings & Valuation
| Gross Revenue | Price/Sales Ratio | Net Income | Earnings Per Share | Price/Earnings Ratio | |
| Plus Therapeutics | N/A | N/A | -$12.98 million | ($1.91) | -0.27 |
| Dyne Therapeutics | N/A | N/A | -$317.42 million | ($3.66) | -5.78 |
Dyne Therapeutics is trading at a lower price-to-earnings ratio than Plus Therapeutics, indicating that it is currently the more affordable of the two stocks.
Profitability
This table compares Plus Therapeutics and Dyne Therapeutics’ net margins, return on equity and return on assets.
| Net Margins | Return on Equity | Return on Assets | |
| Plus Therapeutics | -357.85% | N/A | -117.72% |
| Dyne Therapeutics | N/A | -64.12% | -56.75% |
Volatility & Risk
Plus Therapeutics has a beta of 0.77, meaning that its stock price is 23% less volatile than the S&P 500. Comparatively, Dyne Therapeutics has a beta of 1.16, meaning that its stock price is 16% more volatile than the S&P 500.
Insider & Institutional Ownership
3.3% of Plus Therapeutics shares are owned by institutional investors. Comparatively, 96.7% of Dyne Therapeutics shares are owned by institutional investors. 0.8% of Plus Therapeutics shares are owned by company insiders. Comparatively, 14.1% of Dyne Therapeutics shares are owned by company insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a stock will outperform the market over the long term.
Summary
Dyne Therapeutics beats Plus Therapeutics on 8 of the 13 factors compared between the two stocks.
About Plus Therapeutics
Plus Therapeutics, Inc., a clinical-stage pharmaceutical company, focuses on the development, manufacture, and commercialization of treatments for patients with cancer. Its lead radiotherapeutic drug candidate is rhenium (186Re) obisbemeda, a patented radiotherapy that targets central nervous system cancers and other cancers, including recurrent glioblastoma, leptomeningeal metastases, and pediatric brain cancers. The company also develops Rhenium-188 NanoLiposome Biodegradable Alginate Microsphere that is designed to treat various solid organ cancers comprising primary and secondary liver cancers by intra-arterial injection. It has license agreements with NanoTx, Corp. and The University of Texas Health Science Center at San Antonio. The company was formerly known as Cytori Therapeutics, Inc. and changed its name to Plus Therapeutics, Inc. in July 2019. Plus Therapeutics, Inc. was founded in 1996 and is headquartered in Austin, Texas.
About Dyne Therapeutics
Dyne Therapeutics, Inc., a clinical-stage muscle disease company, operates as a biotechnology company that focuses on advancing therapeutics for genetically driven muscle diseases in the United States. It is developing a portfolio of muscle disease therapeutics, including programs in myotonic dystrophy type 1; duchenne muscular dystrophy; and facioscapulohumeral dystrophy, as well as rare skeletal muscle, and cardiac and metabolic muscle diseases using its FORCE platform that delivers disease-modifying therapeutics. Dyne Therapeutics, Inc. was incorporated in 2017 and is headquartered in Waltham, Massachusetts.
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