RegeneRx Biopharmaceuticals (OTCMKTS: RGRX) and Endo International (NASDAQ:ENDP) are both small-cap medical companies, but which is the superior investment? We will contrast the two businesses based on the strength of their institutional ownership, earnings, risk, profitability, valuation, analyst recommendations and dividends.

Analyst Recommendations

This is a breakdown of recent ratings for RegeneRx Biopharmaceuticals and Endo International, as provided by MarketBeat.

Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
RegeneRx Biopharmaceuticals 0 0 1 0 3.00
Endo International 1 15 4 0 2.15

RegeneRx Biopharmaceuticals currently has a consensus price target of $1.50, indicating a potential upside of 632.42%. Endo International has a consensus price target of $11.59, indicating a potential upside of 48.45%. Given RegeneRx Biopharmaceuticals’ stronger consensus rating and higher possible upside, analysts plainly believe RegeneRx Biopharmaceuticals is more favorable than Endo International.

Earnings and Valuation

This table compares RegeneRx Biopharmaceuticals and Endo International’s gross revenue, earnings per share and valuation.

Gross Revenue Price/Sales Ratio Net Income Earnings Per Share Price/Earnings Ratio
RegeneRx Biopharmaceuticals $90,000.00 249.83 $220,000.00 ($0.01) -20.48
Endo International $4.01 billion 0.43 -$3.35 billion ($22.45) -0.35

RegeneRx Biopharmaceuticals has higher earnings, but lower revenue than Endo International. RegeneRx Biopharmaceuticals is trading at a lower price-to-earnings ratio than Endo International, indicating that it is currently the more affordable of the two stocks.

Risk and Volatility

RegeneRx Biopharmaceuticals has a beta of -2.79, meaning that its stock price is 379% less volatile than the S&P 500. Comparatively, Endo International has a beta of 0.59, meaning that its stock price is 41% less volatile than the S&P 500.

Insider and Institutional Ownership

0.2% of RegeneRx Biopharmaceuticals shares are held by institutional investors. Comparatively, 93.2% of Endo International shares are held by institutional investors. 12.1% of RegeneRx Biopharmaceuticals shares are held by insiders. Comparatively, 0.5% of Endo International shares are held by insiders. Strong institutional ownership is an indication that hedge funds, large money managers and endowments believe a company is poised for long-term growth.

Profitability

This table compares RegeneRx Biopharmaceuticals and Endo International’s net margins, return on equity and return on assets.

Net Margins Return on Equity Return on Assets
RegeneRx Biopharmaceuticals -1,539.62% -23.23% -170.89%
Endo International -126.97% 66.98% 8.38%

Summary

Endo International beats RegeneRx Biopharmaceuticals on 7 of the 13 factors compared between the two stocks.

About RegeneRx Biopharmaceuticals

RegeneRx Biopharmaceuticals, Inc. is a biopharmaceutical company. The Company is focused on the development of a therapeutic peptide, Thymosin beta 4 (Tb4), for tissue and organ protection, repair and regeneration. The Company’s segment is the development and marketing of product candidates based on Tb4, an amino acid peptide. The Company has formulated Tb4 into three product candidates in clinical development: RGN-259, RGN-352 and RGN-137. Tb4 is a synthetic copy of a naturally occurring 43-amino acid peptide that is originally isolated from bovine thymus glands. RGN-259 is its preservative-free eye drop formulation of Tb4. RGN-352 is an injectable formulation to treat cardiovascular diseases, central and peripheral nervous system diseases, and other medical indications that may be treated by systemic administration. RGN-137 is a topical gel for dermal wounds and reduction of scar tissue.

About Endo International

Endo International PLC, formerly Endo Health Solutions Inc. is a specialty healthcare solutions company focused on branded and generic pharmaceuticals, devices and services. The Company has a portfolio of branded pharmaceuticals that includes brands, such as Lidoderm, Opana ER, Voltaren Gel, Percocet, Frova, Supprelin LA, Vantas, Valstar and Fortesta Gel. The Company operates in three segments: Endo Pharmaceuticals, Qualitest and AMS. In June 2014, the Company’s subsidiary, Endo Pharmaceuticals sold its pharmaceutical drug discovery platform to AsanaBioSciences, LLC. In June 2014, Asana BioSciences, LLC, an independent member of Amneal Alliance of Companies, acquired early-stage branded pharmaceutical discovery platform of Endo Pharmaceuticals, a subsidiary of Endo International plc. In June 2014, Trendlines Group acquired intellectual property developed within the framework of an R&D agreement with the Company. In July 2014, it acquired Grupo Farmaceutico Somar.

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