Mosaic ImmunoEngineering (OTCMKTS:CPMV – Get Free Report) and BeyondSpring (NASDAQ:BYSI – Get Free Report) are both small-cap medical companies, but which is the better business? We will compare the two businesses based on the strength of their earnings, profitability, dividends, analyst recommendations, risk, valuation and institutional ownership.
Insider & Institutional Ownership
40.3% of BeyondSpring shares are held by institutional investors. 81.0% of Mosaic ImmunoEngineering shares are held by insiders. Comparatively, 29.3% of BeyondSpring shares are held by insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a company is poised for long-term growth.
Volatility and Risk
Mosaic ImmunoEngineering has a beta of -0.82, suggesting that its stock price is 182% less volatile than the S&P 500. Comparatively, BeyondSpring has a beta of 0.55, suggesting that its stock price is 45% less volatile than the S&P 500.
Analyst Ratings
| Sell Ratings | Hold Ratings | Buy Ratings | Strong Buy Ratings | Rating Score | |
| Mosaic ImmunoEngineering | 0 | 0 | 0 | 0 | 0.00 |
| BeyondSpring | 1 | 0 | 0 | 0 | 1.00 |
Valuation & Earnings
This table compares Mosaic ImmunoEngineering and BeyondSpring”s top-line revenue, earnings per share (EPS) and valuation.
| Gross Revenue | Price/Sales Ratio | Net Income | Earnings Per Share | Price/Earnings Ratio | |
| Mosaic ImmunoEngineering | N/A | N/A | -$920,000.00 | ($0.09) | -6.54 |
| BeyondSpring | $1.75 million | 39.06 | -$11.12 million | ($0.15) | -11.30 |
Mosaic ImmunoEngineering has higher earnings, but lower revenue than BeyondSpring. BeyondSpring is trading at a lower price-to-earnings ratio than Mosaic ImmunoEngineering, indicating that it is currently the more affordable of the two stocks.
Profitability
This table compares Mosaic ImmunoEngineering and BeyondSpring’s net margins, return on equity and return on assets.
| Net Margins | Return on Equity | Return on Assets | |
| Mosaic ImmunoEngineering | N/A | N/A | -761.65% |
| BeyondSpring | N/A | N/A | N/A |
Summary
BeyondSpring beats Mosaic ImmunoEngineering on 5 of the 9 factors compared between the two stocks.
About Mosaic ImmunoEngineering
Mosaic ImmunoEngineering, Inc., a development-stage biotechnology company, focuses on developing and commercializing immunomodulator platform technology for the treatment of cancer and infectious diseases in humans and for veterinary use. Its lead immunotherapy product candidate, MIE-101, a nanoparticle-based treatment derived from cowpea mosaic virus, which is non-infectious in humans and animals. The company was founded in 2020 and is based in Novato, California.
About BeyondSpring
BeyondSpring Inc., a clinical stage biopharmaceutical company, together with its subsidiaries, focuses on the development of cancer therapies. The company's lead asset is the Plinabulin, a selective immunomodulating microtubule-binding agent that has completed Phase III clinical trials for treatment of non-small cell lung cancer (NSCLC); and as an anti-cancer agent, as well as for the prevention of chemotherapy-induced neutropenia. It is also developing Plinabulin in combination with docetaxel vs. docetaxel alone for the treatment of NSCLC and epidermal growth factor receptor wild type. In addition, the company develops Plinabulin in combination with various immuno-oncology agents and chemotherapy or radiation, including; nivolumab, a PD-1 antibody that is has completed phase 1 clinical trials for the treatment of non-small cell lung cancer; ipilimumab, a CTLA-4 antibody for the treatment of extensive-stage small cell lung cancer; in combination with PD-1 or PD-L1 antibodies and radiation for the treatment of various cancers; and pembrolizumab, etoposide, and platinum to treat extensive-stage small cell lung cancer. Further, it engages in the development of three small molecule immune agents in preclinical stages; and a drug discovery platform to develop therapeutic agents from internal research and development efforts and from collaboration. The company was founded in 2010 and is headquartered in Florham Park, New Jersey.
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