Anika Therapeutics (NASDAQ: ANIK) and Trius Therapeutics (NASDAQ:TSRX) are both healthcare companies, but which is the better investment? We will contrast the two businesses based on the strength of their risk, dividends, valuation, profitability, institutional ownership, earnings and analyst recommendations.

Profitability

This table compares Anika Therapeutics and Trius Therapeutics’ net margins, return on equity and return on assets.

Net Margins Return on Equity Return on Assets
Anika Therapeutics 28.23% 13.40% 12.41%
Trius Therapeutics N/A N/A N/A

Valuation and Earnings

This table compares Anika Therapeutics and Trius Therapeutics’ revenue, earnings per share (EPS) and valuation.

Gross Revenue Price/Sales Ratio NetIncome Earnings Per Share Price/Earnings Ratio
Anika Therapeutics $103.38 million 7.77 $32.54 million $2.12 25.86
Trius Therapeutics N/A N/A N/A ($1.60) N/A

Anika Therapeutics has higher revenue and earnings than Trius Therapeutics. Trius Therapeutics is trading at a lower price-to-earnings ratio than Anika Therapeutics, indicating that it is currently the more affordable of the two stocks.

Analyst Ratings

This is a breakdown of current ratings and target prices for Anika Therapeutics and Trius Therapeutics, as reported by MarketBeat.com.

Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Anika Therapeutics 0 0 1 0 3.00
Trius Therapeutics 0 0 0 0 N/A

Anika Therapeutics currently has a consensus price target of $57.00, suggesting a potential upside of 3.98%.

Insider and Institutional Ownership

84.0% of Anika Therapeutics shares are owned by institutional investors. 6.6% of Anika Therapeutics shares are owned by company insiders. Strong institutional ownership is an indication that large money managers, hedge funds and endowments believe a company will outperform the market over the long term.

Summary

Anika Therapeutics beats Trius Therapeutics on 8 of the 8 factors compared between the two stocks.

Anika Therapeutics Company Profile

Anika Therapeutics, Inc. is an orthopedic medicines company. The Company is engaged in developing, manufacturing and commercializing products based on its hyaluronic acid (HA) technology. The Company’s orthopedic medicine portfolio includes ORTHOVISC, MONOVISC, and CINGAL, which alleviate pain and restore joint function by replenishing depleted HA, and HYALOFAST, a solid HA-based scaffold to aid cartilage repair and regeneration. The Company’s therapeutic offerings consist of products in the areas, including Orthobiologics, which includes viscosupplementation and regenerative orthopedic products; Dermal, which includes wound care products; Surgical, which includes products used to prevent post-surgical adhesions, and Other, which includes the Company’s ophthalmic and veterinary products. The Company also offers products made from HA based on two other technologies: HYAFF, which is a solid form of HA, and ACP gel, an autocross-linked polymer of HA.

Trius Therapeutics Company Profile

Trius Therapeutics, Inc. is a biopharmaceutical company focused on the discovery, development and commercialization of antibiotics for life threatening infections. The Company is developing torezolid phosphate, an intraveneous (IV) and oral antibiotic, for the treatment of serious gram-positive bacterial infections, initially for acute bacterial skin and skin structure infections (ABSSSI), and subsequently for other indications. In addition, the Company is developing antibiotics for gram-negative infections using its discovery platform under two contracts: one funded by the National Institute of Allergy and Infectious Diseases (NIAID), a part of the National Institutes of Health (NIH) and the other funded by the Defense Threat Reduction Agency (DTRA), a part of the Department of Defense. In September 2013, Cubist Pharmaceuticals Inc announced that it has completed the acquisition of Trius Therapeutics Inc.

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