Codexis (NASDAQ: CDXS) and Beyondspring (NASDAQ:BYSI) are both small-cap industrial products companies, but which is the superior business? We will compare the two companies based on the strength of their valuation, earnings, dividends, institutional ownership, profitability, analyst recommendations and risk.

Valuation and Earnings

This table compares Codexis and Beyondspring’s revenue, earnings per share (EPS) and valuation.

Gross Revenue Price/Sales Ratio Net Income Earnings Per Share Price/Earnings Ratio
Codexis $48.84 million 8.91 -$8.55 million ($0.65) -13.85
Beyondspring N/A N/A -$12.01 million N/A N/A

Codexis has higher revenue and earnings than Beyondspring.


This table compares Codexis and Beyondspring’s net margins, return on equity and return on assets.

Net Margins Return on Equity Return on Assets
Codexis -76.37% -140.02% -73.00%
Beyondspring N/A N/A N/A

Analyst Recommendations

This is a summary of recent ratings and recommmendations for Codexis and Beyondspring, as reported by MarketBeat.

Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Codexis 0 1 2 0 2.67
Beyondspring 0 0 4 0 3.00

Codexis presently has a consensus price target of $8.33, indicating a potential downside of 7.41%. Beyondspring has a consensus price target of $54.50, indicating a potential upside of 111.73%. Given Beyondspring’s stronger consensus rating and higher possible upside, analysts plainly believe Beyondspring is more favorable than Codexis.

Insider & Institutional Ownership

65.7% of Codexis shares are owned by institutional investors. Comparatively, 1.2% of Beyondspring shares are owned by institutional investors. 9.8% of Codexis shares are owned by company insiders. Strong institutional ownership is an indication that large money managers, endowments and hedge funds believe a stock will outperform the market over the long term.


Beyondspring beats Codexis on 6 of the 10 factors compared between the two stocks.

Codexis Company Profile

Codexis, Inc. is a developer of biocatalysts for the pharmaceutical and fine chemicals markets. The Company’s CodeEvolver protein engineering technology platform, which introduces genetic mutations into genes in order to give rise to changes in the enzymes that they produce, overcomes many of the limitations, allowing customers to evolve and optimize biocatalysts to perform specific and desired chemical reactions at commercial scale. The Company’s pharmaceutical products include enzymes, pharmaceutical intermediates, active pharmaceutical ingredients (APIs) and Codex Biocatalyst Panels and Kits. The fine chemicals market consists of several market verticals, including food and food ingredients, animal feed, flavors and fragrances, and agricultural chemicals. The Company also uses its technology to develop an early stage, enzyme therapeutic product candidate for the treatment of phenylketonuria (PKU) in humans through oral administration.

Beyondspring Company Profile

BeyondSpring Inc. is a global clinical-stage biopharmaceutical company. The Company is focused on the development of cancer therapies. The Company is engaged in advancing its lead product, Plinabulin, into a Phase II/III clinical trial for the reduction of docetaxel chemotherapy-induced severe, grade 4 neutropenia; a Phase II/III clinical trial for the prevention of non-docetaxel chemotherapy-induced severe, grade 4 neutropenia, and a Phase III clinical trial as an anticancer agent in combination with docetaxel in advanced non-small cell lung cancer (NSCLC). Plinabulin has also entered in a Phase I/II clinical trials to investigate its therapeutic potential in combination with the immuno-oncology agent nivolumab. The Company’s BPI-002 program is based on an oral small molecule agent, which induces T-cell activation. The Company’s IkappaB kinase (IKK) program, BPI-003, is based on a small molecule inhibitor of IKK, a protein kinase.

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