Alphatec Holdings (NASDAQ: ATEC) and WaferGen Bio-systems (NASDAQ:WGBS) are both small-cap medical companies, but which is the better investment? We will compare the two companies based on the strength of their profitability, earnings, risk, analyst recommendations, institutional ownership, dividends and valuation.

Analyst Recommendations

This is a summary of recent ratings and recommmendations for Alphatec Holdings and WaferGen Bio-systems, as reported by

Sell Ratings Hold Ratings Buy Ratings Strong Buy Ratings Rating Score
Alphatec Holdings 0 0 2 0 3.00
WaferGen Bio-systems 0 0 0 0 N/A

Alphatec Holdings presently has a consensus target price of $5.50, suggesting a potential upside of 45.12%. Given Alphatec Holdings’ higher possible upside, research analysts clearly believe Alphatec Holdings is more favorable than WaferGen Bio-systems.


This table compares Alphatec Holdings and WaferGen Bio-systems’ net margins, return on equity and return on assets.

Net Margins Return on Equity Return on Assets
Alphatec Holdings -25.13% N/A -31.74%
WaferGen Bio-systems -153.30% -463.27% -111.39%

Institutional and Insider Ownership

18.2% of Alphatec Holdings shares are owned by institutional investors. Comparatively, 49.8% of WaferGen Bio-systems shares are owned by institutional investors. 23.6% of Alphatec Holdings shares are owned by insiders. Comparatively, 5.8% of WaferGen Bio-systems shares are owned by insiders. Strong institutional ownership is an indication that endowments, large money managers and hedge funds believe a company will outperform the market over the long term.

Earnings and Valuation

This table compares Alphatec Holdings and WaferGen Bio-systems’ top-line revenue, earnings per share and valuation.

Gross Revenue Price/Sales Ratio NetIncome Earnings Per Share Price/Earnings Ratio
Alphatec Holdings $120.25 million 0.49 -$29.92 million ($3.01) -1.26
WaferGen Bio-systems N/A N/A N/A ($5.70) -1.21

WaferGen Bio-systems has higher revenue, but lower earnings than Alphatec Holdings. Alphatec Holdings is trading at a lower price-to-earnings ratio than WaferGen Bio-systems, indicating that it is currently the more affordable of the two stocks.


Alphatec Holdings beats WaferGen Bio-systems on 8 of the 9 factors compared between the two stocks.

About Alphatec Holdings

Alphatec Holdings, Inc. is a medical technology company. The Company through its subsidiary, Alphatec Spine, Inc. and its subsidiaries, designs, develops, manufactures and markets products for the surgical treatment of spine disorders. Its product portfolio and pipeline addresses the cervical, thoracolumbar and intervertebral regions of the spine and covers a range of spinal disorders and surgical procedures. Its products include Cervical and Cervico-Thoracic Products, which include Trestle Luxe Anterior Cervical Plate System and Pegasus Anchored Cervical Interbody; Thoracolumbar Fixation Products, which include Arsenal Degenerative System and OsseoScrew Spinal Fixation System; Spinal Spacers, which include Battalion Universal Spacer System and Alphatec Solus Locking ALIF Spinal Spacer; minimally invasive surgery Products, which include Illico Minimally Invasive Surgery System and BridgePoint Spinous Process Fixation System, and Biologics, which include Neocore Osteoconductive Matrix.

About WaferGen Bio-systems

WaferGen Bio-systems, Inc. (WaferGen) is engaged in the development, manufacture and sale of genomic technology solutions for single-cell analysis (SCA) and clinical research. The Company focuses on marketing an open format genetic analysis system, the WaferGen SmartChip System. The Company’s ICELL8 Single-Cell System is a platform that can isolate a range of single cells and process specific cells for analysis, including Next Generation Sequencing (NGS). ICELL8 is based upon the Company’s SmartChip platform, which is also used for profiling and validating molecular biomarkers. The Company’s SmartChip is a micro-fabricated chip comprising a range of massively-parallel micro wells that are physically separated from each other. It offers SmartChip System Capabilities, SmartChip Single-Cell Isolation System, SmartChip Target Enrichment (TE) System and Apollo 324 Library Preparation.

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